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Restylane Refyne and Defyne

Galderma, a leader in cosmetic fillers has announced Refyne and Defyne as the first flexible and natural appearing dermal fillers which move with each contour and movement of your face.

These products are designed to help smooth out smile and laugh lines while maintaining a natural look, thereby creating a beautiful natural filler effect without any visible signs of having an treatments when you smile and show expression.

We are excited to offer these next generation products, while applying the expertise we’ve accumulated through years of using Restylane. Say goodbye to stiff looking cheeks and laugh lines!

newbeauty magazine 2020 award winnerRestylane wins the coveted NEWBEAUTY Best-of Awards three years in a row:
2020 – “Best Filler For Laugh Lines” – Restylane Refyne
2019 – “Best Filler For Laugh Lines” – Restylane Refyne
2018 – “Best Way To Banish Laugh Lines” – Restylane Refyne

What’s the difference?

Refyne is best for mild to moderate lines or volume loss in the lower face; particularly around the mouth and is showing incredible promise for hallows under the eyes.

Defyne is approved for moderate to deep line, volume loss and facial contouring.

refyne and defyne video

Natural Results That Refyne Your Laugh Lines Restylane Refyne logo

Restylane® Refyne is designed to help soften laugh lines (nasolabial folds and marionette lines). This can help you restore a more natural look to your face while maintaining your facial expressions.

The unique cross-linking of the gel in Restylane Refyne is also designed to help support your natural expression—for results that help maintain natural movement when you’re smiling, frowning and even puckering up.

Defyne Your Expression

Restylane Defyne helps smooth out deep laugh lines (nasolabial folds and marionette lines). With an innovative cross-linking technology, Restylane Defyne is able to help restore a more youthful, natural-looking appearance, while helping you maintain your natural expressions.
 

In a clinical study, subjects were evaluated based on perception of the naturalness of facial expressions in motion after 1 month of Restylane Defyne and Restylane Refyne optimal treatment.

• 97% of treated subjects were satisfied with their treatment results
• 97% of treated subjects would do the treatment again
• 95% of treated subjects would recommend the products to a friend

hvme horizontal rule

The Restylane family of fillers include: Restylane   •   Silk   •   Lyft   •   Refyne   &   Defyne   •   Kysse   •   Contour   •   Eyelight

Galderma At-A-Glance Brochure
 
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Kirsten S.
Linda and staff are amazing. I am always very happy with my treatment results. It is apparent that she researches various technologies and techniques. The applications are always evolving with new and improved products. Highly recommended.
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Suzanne P.
Excellent service and an overall pleasant experience. Victoria was professional and knowledgeable. She proposed treatments addressing both my anesthetic and medical concerns.. I could not be happier with the results. Also, the Receptionist, Mattie, was pleasant and efficient. I look forward to future treatments.
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Lisa M.
Hayes Valley is the best! Kate did an incredible job with Dysport removing the wrinkles from my forehead, Sandra gave me great abs and glutes with Emsculpt, and Linda gave me my youthful facial structure back with Sculptra. These women are truly amazing. So glad that I found them!
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Gene V.
I love Hayes Valley Medical and Esthetics! I've been coming for a while now for Botox and filler treatments. Linda is AMAZING! She knows just the right amount of product needed in all the right places to bring out my best facial features. I feel more handsome every time!!

The front desk staff are super sweet and helpful. They always ask exactly what I want and I never feel like I'm being 'upsold' or encouraged to do anything other than what I came in for. I would highly recommend HVME to anybody that is on the unsure about trying some of the services they offer. You won't be disappointed. Thank you!!
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Julie S.
This was my first experience with any filler/injection treatment and it was very pleasant, professional and everyone there made me feel safe, welcome and I felt very knowledgeable coming out of my treatment about what to expect. I will absolutely be back!
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Tina B.
Diana at the front desk is so sweet, the medical assistant was amazing & personable and Kate who did my procedure is my favorite! As I walked out and met my husband, I told him how much I enjoy being there & what a good vibe Hayes has.
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Cher B.
Sheila and Linda took great care of me and I look younger and vibrant.  I do not trust anyone else for injectables.  Linda is careful, thoughtful, and respectful of one’s budget. I have followed her from Marin into SF and I will continue to follow her where ever she practices.
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Emily N.
I highly recommend Hayes Valley Medical & Esthetics!! All the front desk staff are warm, friendly and professional and Denise is the best for laser, she goes above to make you feel comfortable and at ease. Andrea is exceptional at explaining the services they offer. They are the best in SF in my opinion and I do my research!
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Kathleen F.
Excellent customer service, advice, and care. Botox and Microneedling. Melonie is a gem. She is extremely knowledgable, sincere and honest. Everyone here is helpful, They carry a fabulous array of skin products too. I am so pleased with my results!
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Receive 10% off your first treatment at either location!

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